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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BECN1
All Species:
13.64
Human Site:
T143
Identified Species:
20
UniProt:
Q14457
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14457
NP_003757.1
450
51896
T143
L
C
E
E
C
T
D
T
L
L
D
Q
L
D
T
Chimpanzee
Pan troglodytes
XP_511522
450
51866
T143
L
C
E
E
C
T
D
T
L
L
D
Q
L
D
T
Rhesus Macaque
Macaca mulatta
XP_001111932
450
51890
T143
L
C
E
E
C
T
D
T
L
L
D
Q
L
D
T
Dog
Lupus familis
XP_537634
362
42279
K115
Q
E
L
E
E
V
E
K
N
R
K
I
V
A
E
Cat
Felis silvestris
Mouse
Mus musculus
O88597
448
51515
Q177
M
N
E
D
D
S
E
Q
L
Q
R
E
L
K
E
Rat
Rattus norvegicus
Q91XJ1
448
51538
Q177
M
N
E
G
D
S
E
Q
L
Q
R
E
L
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514527
394
45783
A144
R
L
I
Q
E
L
E
A
V
E
Q
S
R
Q
A
Chicken
Gallus gallus
Q5ZKS6
447
51416
T147
T
L
L
D
Q
L
D
T
Q
L
N
I
T
E
N
Frog
Xenopus laevis
Q6GP52
445
51275
K174
M
N
E
D
D
K
E
K
L
E
A
K
L
K
E
Zebra Danio
Brachydanio rerio
P13104
284
32704
S36
K
K
A
A
E
E
R
S
K
Q
L
E
D
D
L
Tiger Blowfish
Takifugu rubipres
NP_001032963
447
51199
T147
T
L
L
D
H
L
D
T
Q
L
N
I
T
E
N
Fruit Fly
Dros. melanogaster
Q9VCE1
422
48852
P151
L
E
Q
Q
R
V
A
P
N
V
E
A
L
D
K
Honey Bee
Apis mellifera
XP_392365
430
49618
E146
Y
L
K
K
L
E
I
E
Q
Q
H
Q
G
H
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786368
415
47747
E147
E
G
R
G
E
S
N
E
D
L
E
K
E
L
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M367
517
58486
V178
L
C
L
E
C
M
R
V
L
S
D
K
L
E
K
Baker's Yeast
Sacchar. cerevisiae
Q02948
557
63242
I188
I
C
Q
D
C
C
N
I
L
I
N
R
L
K
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.7
78.8
N.A.
97.3
97.3
N.A.
76.8
91.7
88.6
20
81.1
49.1
56.4
N.A.
57.5
Protein Similarity:
100
99.7
99.7
79.5
N.A.
98
98.2
N.A.
81.5
94.6
94.8
36.4
89.5
67.7
69.3
N.A.
71.5
P-Site Identity:
100
100
100
6.6
N.A.
20
20
N.A.
0
20
20
6.6
20
20
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
20
N.A.
53.3
46.6
N.A.
20
40
46.6
20
40
46.6
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
28
24.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.2
44.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
0
7
7
0
0
7
7
0
7
7
% A
% Cys:
0
32
0
0
32
7
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
32
19
0
32
0
7
0
25
0
7
32
0
% D
% Glu:
7
13
38
32
25
13
32
13
0
13
13
19
7
19
32
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
13
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
7
0
0
7
0
% H
% Ile:
7
0
7
0
0
0
7
7
0
7
0
19
0
0
0
% I
% Lys:
7
7
7
7
0
7
0
13
7
0
7
19
0
25
13
% K
% Leu:
32
25
25
0
7
19
0
0
50
38
7
0
57
7
7
% L
% Met:
19
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
0
0
0
13
0
13
0
19
0
0
0
13
% N
% Pro:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% P
% Gln:
7
0
13
13
7
0
0
13
19
25
7
25
0
7
0
% Q
% Arg:
7
0
7
0
7
0
13
0
0
7
13
7
7
0
0
% R
% Ser:
0
0
0
0
0
19
0
7
0
7
0
7
0
0
7
% S
% Thr:
13
0
0
0
0
19
0
32
0
0
0
0
13
0
19
% T
% Val:
0
0
0
0
0
13
0
7
7
7
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _